Indifferent and powerful Yasson.

Lightwheel MarkKarrie's Basic Attacks and skills apply a stack of Lightwheel Mark on hit. Once a target has 5 stacks of Lightwheel Marks, the marks will turn into a lightwheel, dealing True Damage equal to 5 (+1% Extra Physical Attack)% of the target's Max HP to them (only up to 300 damage against Creeps).
Tanks such as Tigreal and Fredrinn that take more damage from her HP percent attacks.
Long range heroes such as Xavier, Layla and Nana due to Karrie's medium range.